PatchMD Biotin Plus Topical Patch Biotin is an important B-Vitamin known to support healthy hair, skin and nails. Biotin also supports energy production.* How To Use Apply patch daily to an area with little or no hair, i.e., shoulder, back or hip. For best results, it is recommended to wear PatchMD patches for 8 hours. There is no additional benefit wearing the patch longer than 8 hours. Avoid using any lotion or cream in the same area as it will inhibit absorption. Patch is not waterproof. Patches May also be worn overnight while you sleep. Multiple patches can be worn at the same time. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.