Bio-Simplex Media Bottle Assembly Systems Bio-Simplex Media Bottle Assembly Systems . The closed-system design includes a PETG Square Media Bottle, two port EZ Top closure assembly (C-Flex TPE resin tubing ) with a 0.2 ?M vent filter, notched dip tube, and a polyethylene cap. The system is engineered to ensure an unobstructed fluid path, extremely low levels of extractables, and a secure elastomeric seal between closure and bottle. Economically designed for the single-use market, these systems are easily used with sterile connecting devices and thermal tubing sealers. They are sold double-bagged and gamma irradiated to achieve a Sterility Assurance Level (SAL) of 10-6 per ANSI/AAMI/ISO 11137 Many in stock ...message us if quantity needed exceeds list number.